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Top 5 Weight Loss Medications: A Comprehensive Overview

Explore some of the top platforms that provide online prescriptions for weight loss medications. Discover the ideal service that matches your health goals, lifestyle, and personal preferences.

"You have the power to achieve your weight loss goals — just a few months of the right medication, along with adjustments to your diet and exercise routine, can set you on the path to lasting success."

Editorial Note: We earn a commission from partner links displayed on this page, which impacts how and where their offers appear.

1

9.8

EXCELLENT

RemedyMeds

  • Instant pre-approval with a 2-minute quiz
  • No insurance needed
  • Lose up to 1.5% of body fat per week
  • Access to Semaglutide® or Tirzepatide®, get $75 off first month
  • Free medication delivery or local pickup options
  • Fast online doctor consultations via mobile app

9.8

EXCELLENT
Visit Site Go to RemedyMeds

2

9.6

EXCELLENT

Remote Pharmacy

  • Free 5-minute quiz for pre-approval
  • Access to generic versions of Ozempic, Wegovy, and Zepbound
  • Prescriptions issued within 24 hours, medication shipped within 48 hours

9.6

EXCELLENT
Visit Site Go to Remote Pharmacy

3

9.6

EXCELLENT

G-Plans

  • Free 5-minute quiz for pre-approval, no insurance required
  • Access to Ozempic, Wegovy, and other weight loss medications
  • 92% of users have achieved lasting results

9.6

EXCELLENT
Visit Site Go to G-Plans

4

9.4

VERY GOOD

SkinnyRx

  • Monthly delivery of GLP-1 medications with free shipping
  • Same active ingredient as Wegovy®
  • Doctor-prescribed treatment plan

9.4

VERY GOOD
Visit Site Go to SkinnyRx

5

9.2

VERY GOOD

Get Thin MD

  • Personalized plans tailored to your unique weight loss goals
  • Long-term success without yo-yo dieting
  • Achieve and maintain a healthier lifestyle

9.2

VERY GOOD
Visit Site Go to Get Thin MD

6

9.2

VERY GOOD

Ro

  • Achieve 15% to 20% body weight loss
  • Check eligibility for Ozempic, Wegovy, or Zepbound online
  • Insurance concierge service to assist with costs

9.2

VERY GOOD
Visit Site Go to Ro

7

9.2

VERY GOOD

NOOM Weight + Med

  • Enhance Noom’s core weight loss program for sustainable results
  • Combines weight loss medication with behavior change techniques
  • Routine check-ins with clinicians

9.2

VERY GOOD
Visit Site Go to NOOM Weight + Med

8

9.1

GOOD

LifeMD

  • Save 50% on FDA-approved Zepbound, Wegovy, and more
  • Up to 20% weight loss with medication and behavior changes
  • Insurance assistance and alternative options available

9.1

GOOD
Visit Site Go to LifeMD

9

9.0

GOOD

Henry Meds

  • Medication shipped within 2 days
  • Same active ingredient as Ozempic, no injections needed
  • 30-day money-back guarantee

9.0

GOOD
Visit Site Go to Henry Meds

10

8.9

GOOD

Hers

  • Personalized treatments, including GLP-1s and oral medications
  • Medication as low as $79/month if prescribed
  • Unlimited check-ins and medication adjustments, no insurance required

8.9

GOOD
Visit Site Go to Hers

Weight loss is a challenging journey, and for many, diet and exercise alone aren't enough to reach their goals. That's where weight loss medications can make a difference.

Here's a guide to some of the most effective prescription options currently available.


1. Semaglutide (Wegovy)

Takeaway: Semaglutide is unique for its potent impact on appetite regulation, making it particularly effective for those who need significant weight loss results.

Semaglutide, known by the brand name Wegovy, is a medication that has been making waves in the weight loss community. Originally developed for type 2 diabetes, it works by mimicking a hormone that targets areas of the brain involved in regulating appetite and food intake. Clinical studies have shown it can help individuals lose a significant amount of weight when combined with a reduced-calorie diet and increased physical activity.


2. Phentermine-Topiramate (Qsymia)

Takeaway: Qsymia stands out for its dual-action formula that not only suppresses appetite but also enhances feelings of fullness, making it ideal for those battling persistent hunger.

Qsymia is a combination of two drugs: phentermine, an appetite suppressant, and topiramate, which is used to treat migraines and seizures but also helps with weight loss. Together, these medications work to decrease appetite and promote a feeling of fullness, aiding in weight loss efforts. It's particularly effective for those who struggle with controlling hunger.


3. Naltrexone-Bupropion (Contrave)

Takeaway: Contrave is particularly beneficial for those who need to address emotional eating and cravings, thanks to its unique focus on the brain's reward system.

Contrave combines two drugs, naltrexone and bupropion, which target the brain's hunger and reward system. Naltrexone is commonly used to manage alcohol and opioid dependence, while bupropion is an antidepressant that also helps with smoking cessation. When used together, these drugs can help reduce cravings and manage emotional eating.

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UNLIMITED 24/7 MESSAGING

RemedyMeds: 15% Average Reduction in Body Weight

Get Started On RemedyMeds' Website

4. Liraglutide (Saxenda)

Takeaway: Saxenda is similar to Semaglutide but offers a slightly different GLP-1-based approach, making it a strong option for those seeking alternatives within the same medication class.

Liraglutide, sold under the brand name Saxenda, is another medication initially developed for type 2 diabetes. It works similarly to Semaglutide by mimicking the GLP-1 hormone that controls appetite. Saxenda has been shown to help with significant weight loss when used in conjunction with lifestyle changes.


5. Orlistat (Alli/Xenical)

Takeaway: Orlistat is unique in its non-systemic approach, focusing on fat absorption in the digestive tract, making it an option for those seeking a medication that works locally rather than systemically.

Orlistat is different from the other medications on this list as it works by blocking the absorption of fat in the digestive system. It's available in both prescription strength (Xenical) and over-the-counter (Alli). By preventing fat from being absorbed, Orlistat can help reduce overall calorie intake, which is essential for weight loss.


How to Choose the Right Medication

Instead of just selecting any medication, it's essential to find the one that aligns with your long-term health goals. Remember, weight loss medications are most effective when combined with a balanced diet, regular physical activity, and good sleep. Consult with your healthcare provider to ensure you're on the right path to sustainable success.


Why Weight Loss Medication is Just One Piece of the Puzzle

Weight loss medications can be a valuable tool in your journey, but they are not a quick fix. Lasting results come from integrating medication with lifestyle changes such as improved nutrition, increased physical activity, and better sleep habits. While some may use these medications for a short period, the key is to build a foundation for long-term health.

We earn a commission from partner links displayed on this page, which impacts how and where their offers appear.
UNLIMITED 24/7 MESSAGING

RemedyMeds: 15% Average Reduction in Body Weight

Get Started On RemedyMeds' Website

Your Path to Lasting Weight Loss: More Than Just Medication

Embarking on a weight loss journey with medication can provide a great boost, but it's vital to maintain a holistic approach. Combining the medication with positive changes in diet, exercise, and sleep can lead to lasting success. Many people find that after a few months of medication, they are better equipped to continue their progress independently.

Your first step should be consulting your doctor. They can discuss the pros and cons of medication and help you choose the best plan for your needs.


Sources

Footnotes

  1. Wilding JPH, Batterham RL, Calanna S, et al. Once-Weekly Semaglutide in Adults with Overweight or Obesity. New England Journal of Medicine. 2021;384(11):989-1002.

15% Average Reduction in Body Weight

9.8

EXCELLENT